"I'm just thrilled I have dental," Hathaway joked on stage.
But in the already-tight best actress race, Jennifer Lawrence made things a little more interesting in winning for the drama "Silver Linings Playbook." The 22-year-old plays a damaged young widow opposite Bradley Cooper, whose character is fresh out of a mental institution. Jessica Chastain, the winner at the Golden Globes, has been her main competition as a driven CIA operative searching for Osama bin Laden in "Zero Dark Thirty."
Lawrence said on stage that she got her SAG card at 14 — which was only eight short years ago — for a promo for the MTV reality series "My Super Sweet 16," which she said felt like the best day of her life.
"And now I have this naked statue which means that some of you even voted for me, and that is an indescribable feeling," she said.
On the television side, the popular PBS series "Downton Abbey" bested more established shows like "Mad Men" to win the TV drama cast award in just its first nomination. "Modern Family" won the comedy cast prize for the third straight year.
And Dick Van Dyke received the guild's life-achievement award, an honor he presented last year to his "The Dick Van Dyke Show" co-star, Mary Tyler Moore.
After receiving a lengthy standing ovation from the audience, he asked his fellow actors, "Aren't we lucky that we found a line of work that doesn't require growing up?"