Louisville forward Wayne Blackshear fell to the floor and Behanan looked as if he was going to be sick on the court, kneeling on his hands and feet. Luke Hancock patted Ware's chest as doctors worked on the sophomore and Smith walked away, pulling his jersey over his eyes. The arena was silent, and several fans wept and bowed their heads.
Pitino had tears in his eyes as he tried to console his players. Dieng draped an arm around the shoulders of Smith, who repeatedly wiped at his eyes and shook his head. The Cardinals (33-5) gathered at halfcourt to try and regroup before Pitino called them over to the sideline, saying Ware wanted to talk to them before he left.
"Basically, the bone popped out of the skin. It broke in two spots," Pitino said. "Remember the bone is six inches out of his leg, and all he's yelling is 'Win the game, win the game.' I've never seen anything like that."
News of the injury dominated social media. Joe Theismann whose NFL career ended with a horrific broken leg, said on Twitter, "Watching Duke/ Louisville my heart goes out to Kevin Ware."
Fans chanted "Kevin! Kevin" as Ware was loaded onto the stretcher, and Pitino wiped away tears again as Ware was wheeled off the court.
"That was a tough one," Pitino said.
Play resumed about 10 minutes later, but it was clear the Cardinals' minds were elsewhere. They missed four of their next five shots along with two free throws, and were uncharacteristically sloppy. But they regrouped after a timeout, with Smith's finger roll sparking a 12-6 run to finish the half that gave them a 35-32 lead.
Smith picked up where he left off at the start of the second half, making all three free throws after being fouled on a 3-point attempt to give Louisville a 38-32 lead, its largest of the game to that point.