The game remained scoreless until the seventh, right after Colin Hanks, the son of actor Tom Hanks — a former peanut vendor at the nearby Oakland Coliseum — sang "Take Me Out to the Ball Game" on the field.
Pence led off with a single and Fister departed, getting lots of hugs in the dugout. Rookie reliever Drew Smyly walked Brandon Belt on a full-count pitch and Blanco's bunt loaded the bases with no outs.
The Tigers kept their infield back up the middle, and had no play at the plate on Crawford's bouncer.
"We felt like we played double-play depth because we felt like we couldn't give them two runs. That's why we did that, and we got the double play," Leyland said.
"To be honest with you, we were absolutely thrilled to come out of that inning with one run. Absolutely thrilled. I mean, we had to score anyway."
Pence added the insurance run the next inning with his flyball off Octavio Dotel.
"We played good small ball today," Pence said. "We played a great game of baseball, had outstanding pitching and great defense and we found a way to get it done."
Of the 52 teams to take a 2-0 lead in the World Series, 41 have gone on to win the title. That includes 14 of the last 15 teams with that advantage.
"I'm not sure, and I haven't done any studies on it," Giants reliever Jeremy Affeldt said, "but statisically it's always better to be 2-0 than 1-1 or 0-2. I'm just guessing."
Fielder and the Tigers came up inches short of taking an early lead, the result of yet another alert play by Scutaro and a dubious decision by third base coach Gene Lamont.