JOPLIN, Mont. (AP) — At least three people were killed Saturday afternoon when an Amtrak train that runs between Seattle and Chicago derailed in north-central Montana, toppling several cars onto their sides, authorities said.

Billions more in profits are at stake for some vaccine makers as the U.S. moves toward dispensing COVID-19 booster shots to shore up Americans' protection against the virus.

SACO, Maine (AP) — Angry over being fired, a former employee slashed the tires of his boss' vehicle and still held the knife when police officers arrived.

CHICAGO (AP) — Austin Moody wanted to apply his cybersecurity skills in his home state of Michigan, teaming up with investigators for the State Police to analyze evidence and track down criminals.

NEW LONDON, Conn. (AP) — Kelli Normoyle was nervous as she arrived at the Coast Guard Academy campus in Connecticut in 2008. She had come out as a lesbian to a few friends near the end of high school, but she faced a military environment where "don't ask, don't tell" was still the policy pro…

AMELIA, La. (AP) — When Hurricane Ida was brewing in the Gulf of Mexico, the grass was chest high and the warehouse empty at this lot in southeastern Louisiana. Within days, electric officials transformed it into a bustling "tent city" with enormous, air-conditioned tents for workers, a grav…

COLLIERVILLE, Tenn. (AP) — A gunman who killed one person and wounded 14 others in a Tennessee grocery store did not appear to target anyone specifically as he rampaged through the building on a sunny Thursday afternoon, police said. The entire shooting was over within minutes as first respo…

WASHINGTON (AP) — Many Americans struggling to feed their families over the past pandemic year say they have had difficulty figuring out how to get help and had trouble finding healthy foods they can afford.

The Centers for Disease Control and Prevention on Thursday endorsed booster shots for millions of older or otherwise vulnerable Americans, opening a major new phase in the U.S vaccination drive against COVID-19.

NEW YORK (AP) — Amid the Boy Scouts of America's complex bankruptcy case, there is worsening friction between the BSA and the major religious groups that help it run thousands of scout units. At issue: the churches' fears that an eventual settlement — while protecting the BSA from future sex…

COLLIERVILLE, Tenn. (AP) — A shooting at a Tennessee grocery store left one person dead and 12 others injured Thursday afternoon, and the shooter was subsequently found dead of an apparent self-inflicted gunshot wound at the store in an upscale suburb of Memphis, authorities said.

WASHINGTON (AP) — The number of Americans applying for unemployment aid rose last week for a second straight week to 351,000, a sign that the delta variant of the coronavirus may be disrupting the job market's recovery, at least temporarily.

NASHVILLE, Tennessee (AP) — A top Southern Baptist Convention committee agreed Tuesday to fund a third-party investigation into its handling of sexual abuse allegations but held off on waiving its attorney-client privilege for the probe, delaying for the future a decision seen as a key deman…

An influential panel of advisers to the Centers for the Disease Control and Prevention convened on Wednesday to debate which Americans should get COVID-19 booster shots and when — a question that has proved more contentious than the Biden administration apparently expected.

LONDON (AP) — Johnson & Johnson said Tuesday that a booster of its one-shot coronavirus vaccine provides a stronger immune response months after people receive a first dose.

Stocks rose modestly in morning trading on Wall Street Tuesday, making up some of the ground they lost in a sharp pullback a day earlier.

ST. PETERSBURG, Fla. (AP) — Police on Monday swarmed the home of a young man wanted for questioning in the disappearance of his girlfriend, Gabby Petito, whose body was apparently discovered over the weekend at a Wyoming national park.

THREE RIVERS, Calif. (AP) — Two lightning-sparked wildfires in California merged and made a run to the edge of a grove of ancient sequoias, momentarily driving away firefighters as they try to protect the world's tallest tree by wrapping its base in protective foil.

CAPE CANAVERAL, Fla. (AP) — Four space tourists safely ended their trailblazing trip to orbit Saturday with a splashdown in the Atlantic off the Florida coast.

WASHINGTON (AP) — It was an hour President Joe Biden would no doubt like to forget.

WASHINGTON (AP) — The fence around the Capitol is back up. The District of Columbia's police department is at the ready. The U.S. Capitol Police have requested assistance from nearby law enforcement agencies including the National Guard.

WASHINGTON (AP) — The Pentagon retreated from its defense of a drone strike that killed multiple civilians in Afghanistan last month, announcing Friday that an internal review revealed that only civilians were killed in the attack, not an Islamic State extremist as first believed.

WASHINGTON — The federal government is spending $2.1 billion to improve infection control procedures in health care settings, aimed at preventing the transmission of diseases inside hospitals, dialysis centers and other facilities.

WASHINGTON (AP) — An influential federal advisory panel has soundly rejected a plan to offer Pfizer booster shots against COVID-19 to most Americans.

WASHINGTON (AP) — Allies of Donald Trump are mounting a Saturday rally at the U.S. Capitol, aimed at supporting what they call the "political prisoners" of the Jan. 6 insurrection — about 60 people held behind bars of the more than 600 charged in the deadly riot.

RUSSELLVILLE, Ark. (AP) — A former Arkansas sheriff's deputy was charged Friday with manslaughter in the fatal shooting of a white teenager whose death has drawn the attention of national civil rights activists.